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It's hard to know when to give up on a goal, especially when you've invested so much time, effort and resources into it. Here are 7 signals you might be ready to move on.

While Health Secretary Robert F. Kennedy, Jr., dismantles the federal institutions that set vaccine policy, states like Colorado are changing laws and regulations in an effort to preserve access to vaccines.

(Image credit: David Zalubowski)

Some 154 million people in the United States get health care through their employer — and for many, their costs are about to go way up.

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Four prosecutors who worked on Capitol riot cases have found a way to continue public service after leaving the Justice Department. They're all colleagues again.

How much security at a campus event is enough? Campus police are mulling the question.

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Though the FDA narrowed criteria for the shots, many people still want them, to avoid illness and protect vulnerable family members. Some are turned down at the pharmacy or have to jump through hoops.

(Image credit: Therese McRae; Stephan Neidenbach; and Jason Mitton)

The firing of Kevin Struthers is the latest in a line of dismissals and resignations at the D.C. arts behemoth.

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The change will allow certain nominees to be confirmed in groups rather than by individual vote. It follows months of GOP complaints that Democrats were dragging out the confirmation process.

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Charlie Kirk's followers are in shock and grief over his assassination. As they try to make sense of his killing, many are also asking what's next for the movement he started.

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A Czech playwright introduced the word to English in the 1920s. But back then, it wasn't analogous to machinery. New interpretations of the robot reflect a modernity once skewered by the writer.

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Hotels have accessible rooms for wheelchair users. If you or someone you know has experienced problems with those rooms, we'd like to hear about it.

Some conservative influencers mourned Kirk's loss, even as others quickly blamed the left.

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A historic conviction: Brazil's Supreme Court delivers a majority vote to convict former President Jair Bolsonaro over a plot to overthrow the government.

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A plane carrying more than 300 workers from South Korea who were detained during an immigration raid at a battery factory in Georgia last week left Atlanta around noon Thursday, bound for South Korea.

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Routh is charged with attempting to assassinate a presidential candidate. A conviction carries a maximum penalty of life in prison. Routh, who is not a lawyer, is representing himself in this case.

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Rates saw the biggest one-week drop in a year, spurring a spike in new purchase and refinance applications.

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Winner was working at the NSA in 2017 when she leaked a classified document to the press. Soon after, the FBI showed up at her door. Winner's new memoir is I Am Not Your Enemy.

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The killing of conservative activist Charlie Kirk Wednesday at a college in Utah is the latest in a series of politically motivated violent acts just in recent months.

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New research estimates that as many as 2.2 million more people could die of tuberculosis if U.S. cuts to foreign aid become permanent.

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Inflation accelerated in August as Americans paid more for gasoline and groceries. Over the last 12 months, consumer prices have risen 2.9%.

(Image credit: Frederic J. Brown)